The Ginkgo Flavonides

The Ginkgo the interest of researchers after resisting the aerial attack of the atomic bomb in the city of Hiroshima despertou and Japan, when it came back to sprout under the ruins of the devastada city. The Ginkgo that is part of the millenarian Chinese therapeutical armory, adapta very well to the urban characteristics and in tempered climate, not being demanding with ground and resisting very well the weighed pollution, ambient insects, fungos, bacteria, plague, factors and virus (HILLEBRAND; OLIVEIRA, 2004). 3.2. Chemical constituent The leaf is the used raw material more for attainment of compresses, thick and dry teas, extracts, until products optimized in solid pharmaceutical forms. The Ginkgo contains two groups of farmacologicamente important chemical substances: known diterpenos as gincoldeos and flavonides (BITENCOURT; MAYER; ZUFFELATO, 2008). The constituent are gotten through diverse solvent and reacting destined to purificar them through inactive substance elimination undesirable, thus guaranteeing the quality of its endoteliais farmacolgicas characteristics (BATISTUZZO; ITAYA; ETO, 2006). The standardized extract of Ginkgo EGb761, must at least contain 24.0% of flavonides and 6% of terpenides. The available capsules deGinkgo in the market frequently are prepared in the concentration of 40, 80 or 120 mg.

Apresenta a great variety of chemical composites including alkalis, lipdios, esteris, benzenos, carotenides, fenilpropanis and carboidratos. Being the main ones, flavonides, esters of the acid cumrico, glicosdicos, catequinas and protocanidinas. The concentration of flavonides is of approximately 0.8%, and characteristic the only ginkolideos are constituent of the Ginkgo.